Evaluation of lactic acid ferment lysate for the management of oily skin: impact on sebum, hydration, and microbiota.

Nominally highly significant differences were observed at Day 30 and Day 60 compared with baseline (nominal P < 0.01).Representative photographic evaluations ( Figure 2 ) confirmed a progressive decline in porphyrin fluorescence over the 60-day period, an exploratory finding suggesting reduced sebaceous gland activity on the cheeks in association with cream application. 3.1.3 Skin pores Detailed scores on skin pore metrics from baseline to endpoint are presented in Supplementary Table 2 .

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Nominally significant differences in bacterial composition abundance were observed at both phylum and genus levels: Staphylococcus , Cutibacterium , and Rhodocytophaga were enriched in the D0 group, while Streptococcus (genus) and Lactobacillales (order) showed significantly higher relative abundance in the D60 group (nominal P < 0.05).

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