Barely Significant
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Correlation between prognostic nutritional index and oral mucositis in patients with lung adenocarcinoma treated with almonertinib: a multicenter prospective study.

Front Nutr · 2026 · PMC13279082 · PMID 42325533

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a decreasing trendno p-value reported
Concurrently, we observed that as PNI levels increased, carcinoembryonic antigen (CEA) levels and clinical staging showed a decreasing trend, while total protein, albumin, and hemoglobin levels gradually increased.

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However, after adjusting for all potential confounding factors (Model 3), although a certain nonlinear trend was still observed, this relationship did not reach statistical significance ( P for Nonlinear > 0.05) ( Figure 4C ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.