Cardiovascular Outcomes in Patients With Deferred and Performed Coronary Revascularization Based on Intracoronary Physiology: A Systematic Review and Meta-Analysis.

Another important limitation that likely contributed to the high degree of heterogeneity and the trend toward significance in the random‐effects model analysis for major adverse cardiovascular events, MI, and unplanned revascularization (which reached significance in the sensitivity analysis using fixed‐effects model) is the variability in end point definitions (Table S9 ).

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For major adverse cardiovascular events (IRR, 1.15 [95% CI, 0.99–1.34]; P =0.07) and myocardial infarction (IRR, 1.24 [95% CI, 0.95–1.61]; P =0.11), the associations did not reach statistical significance.

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