Clinical Safety Profile of Bruton's Tyrosine Kinase (BTK) Inhibitors in Chronic Lymphocytic Leukaemia: A Real-World Ambispective Study From India.

Cureus · 2026 · PMC13280304 · PMID 42326189

Europe PMC DOI

hedged sentence

0.0700

closest p · 1.4× alpha

0.0700

boldest claim

The sentences

did not reach statistical significancep = 0.07so close (0.05 < p ≤ 0.1)

Patients who achieved early hematologic normalisation within four months demonstrated a numerically longer median PFS (18 months) compared with those with delayed normalisation (12 months); however, this difference did not reach statistical significance (p = 0.07).

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