Barely Significant
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Plasma neurofilament light chain and regional brain atrophy mediate the association of neuropsychiatric symptoms with cognition in Alzheimer's disease: evidence from two population-based studies.

Psychol Med · 2026 · PMC13280697 · PMID 42294788

Europe PMCDOI
1
hedged sentence
0.0500
closest p · 1.0× alpha
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boldest claim

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nominally significantP < 0.05actually significant
Plasma NFL alone (Pathway 3) showed nominally significant mediation effects for ADAS13, CDRSB, MEM, and LAN (total indirect effect: all uncorrected P < 0.05) ( Figure 2IV .A, B; Table S9); however, after FDR correction, only the mediation effect on MEM remained significant ( P < 0.05).

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