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Combination Topical Antioxidant Protocol Enhances Laser‐Induced Improvement in Facial Pigmentation and Photoaging: A Prospective, Split‐Face Trial

J Cosmet Dermatol · 2026 · PMC13281373

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For the erythema index, both groups demonstrated reductions of 6.67% and 6.15% at Week 8 for the CEF + RGN6 and CEF groups, respectively; however, these changes did not reach statistical significance in any analyses (Figure 3D ). 3.4 Adverse Events The treatment procedures and test products were generally well‐tolerated throughout the study period.

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