Risk Factors for Subtherapeutic Exposure and Hepatotoxicity Threshold of Posaconazole: A Real-World Study in Chinese Patients with Invasive Pulmonary Fungal Infection.

Although limited by the small sample size of infection events, this difference did not reach statistical significance ( P =0.423).

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Compared with the first to third quartile groups (trough concentration range 0.30–1.94 mg/L), the incidence of most treatment-related adverse events showed an increasing trend in the fourth quartile group (range 1.95–5.20 mg/L).

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