Barely Significant
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Association of high-risk CT coronary artery plaque features with major adverse cardiovascular events: a prespecified secondary analysis of the DISCHARGE trial.

Eur Radiol · 2026 · PMC13282328 · PMID 41686241

1
hedged sentence
0.0680
closest p · 1.4× alpha
0.0680
boldest claim

The sentences

did not reach statistical significancep = 0.068so close (0.05 < p ≤ 0.1)
HRP alone was also significantly associated with MACE (HR: 3.98, 95% CI: 1.02–15.5, p = 0.047), whereas obstructive CAD alone showed similar effect sizes but did not reach statistical significance (HR: 3.99, 95% CI: 0.90–17.6, p = 0.068) compared with those without HRP or obstructive CAD (Supplementary Table 11 ).

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