Intra-coronary imaging and transcriptomics of calcified nodules before and after intensive lipid-lowering therapy: a YELLOW III substudy.

Eur Heart J Imaging Methods Pract · 2026 · PMC13282941 · PMID 42325865

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0.0570

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0.0570

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showed a trendP = 0.057so close (0.05 < p ≤ 0.1)

In the calcium surrounding CNs, nodules with lipid signal demonstrated a modest but statistically significant increase in arc (40.8 ± 13.1 to 43.9 ± 13.5°; Δ + 2.78 ± 1.18, P = 0.018), whereas depth showed a trend toward increase (0.65 ± 0.25 to 0.69 ± 0.26 mm; Δ + 0.04 ± 0.02, P = 0.057).

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