Barely Significant
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Comorbidity of Allergic Asthma and Rhinitis and High Allergen-Specific IgE are Risk Factors for Systemic Reactions to House Dust Mite Immunotherapy in Children.

J Asthma Allergy · 2026 · PMC13282978 · PMID 42326971

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Although there is an increasing risk compared to children with simple AR (OR=1.62), the difference did not reach statistical significance.

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an increasing trendno p-value reported
Compared to patients with pure AR, the risk of adverse reactions in AA+AR patients showed an increasing trend; however, this difference was not statistically significant (OR = 1.62, 95% CI: 0.92–2.85, p = 0.094).

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