Hypertension Treatment with Angiotensin Receptor Blockers and Other Antihypertensive Agents: A Real-World Registry from a High-Volume Specialized Center Over TwoDecades.

Fixed combination therapies with either ACE inhibitors or ARBs plus thiazide or thiazide-like diuretics were frequently used before the publication of 2013 ESH/ESC [ 30 ] hypertension guidelines [ 30 ], though they showed a trend toward reduction after the publication of 2013 ESH/ESC [ 30 ] and, mostly, 2018 ESC/ESH [ 31 ] hypertension guidelines.

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