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TPPU protects against seizures and seizure-associated comorbidities by inhibiting the Akt/mTOR signaling pathway in KA-induced convulsant mice.

Front Immunol · 2026 · PMC13283869 · PMID 42338596

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showed a trendno p-value reported
During the 5-day training period, KA-treated mice showed a trend toward longer escape latencies compared with both the control and TPPU-treated groups ( Figures 1J, K ).

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