Development and validation of a risk stratification model for cardiovascular disease in patients with radiographic axial spondyloarthritis (r-axSpA): a retrospective study.

Front Med (Lausanne) · 2026 · PMC13283871 · PMID 42338935

Europe PMC DOI

hedged sentences

0.0740

closest p · 1.5× alpha

0.0740

boldest claim

The sentences

borderline significanceP = 0.074so close (0.05 < p ≤ 0.1)

Logistic regression suggested a linear inverse association (OR = 0.982), while RCS revealed a U-shaped pattern with borderline significance ( P = 0.074).

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did not reach statistical significanceno p-value reported

Because the nonlinear trend did not reach statistical significance and the ascending limb of the U-shaped curve was based on limited observations, ALP was entered as a linear term in the final logistic regression model to maintain parsimony and avoid overfitting.

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