Barely Significant
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Assessment of 16S rRNA sequencing for analysis of circulating microbial DNA in colorectal cancer patients-proof of concept and early changes during experimental chemoimmunotherapy.

Front Microbiol · 2026 · PMC13283987 · PMID 42338885

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hedged sentence
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closest p · 3.0× alpha
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boldest claim

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did not reach statistical significancep = 0.15not close (p > 0.1)
However, the latter explained a larger proportion of the overall cmDNA diversity (R 2 = 49.4%), although this did not reach statistical significance ( p = 0.15).

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