Comparing the Efficacy and Safety of PRP and PRF on Periorbital Skin Quality: A Randomized Split‐Face Clinical Trial

J Cosmet Dermatol · 2026 · PMC13284528

Europe PMC

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an increasing trendno p-value reported

3.1 Biometric Assessment As shown in Table 1 , among the biometric indices of the PRF group, mean colorimeter changes between baseline and 7 months ( p = 0.048) demonstrated statistically significant improvement, although an increasing trend was observed at all follow‐up time points.

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a decreasing trendno p-value reported

Although a decreasing trend was observed at every follow‐up in transepidermal water loss (Tewameter), the change was not statistically significant.

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did not reach statistical significanceno p-value reported

Erythema decreased at all follow‐up visits but did not reach statistical significance.

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