Discovery of a preliminary urinary metabolite panel for Parkinson's disease: a pilot study using paired patient-spouse samples and machine learning consensus.

Front Neurol · 2026 · PMC13286780 · PMID 42344002

Europe PMC DOI

hedged sentence

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closest p · 1.4× alpha

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boldest claim

The sentences

did not reach statistical significancep = 0.07so close (0.05 < p ≤ 0.1)

Consistent with the matched-pair design, gender distribution showed male predominance in PD patients (3 females/12 males) versus female predominance in controls (12 females/3 males), though this difference did not reach statistical significance by Fisher’s exact test ( p = 0.07).

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