However, in the fully adjusted model for confounders, the association between eGFR < 30 mL/min/1.73 m 2 and in-hospital mortality did not reach statistical significance.
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Association of estimated glomerular filtration rate and in-hospital mortality in patients hospitalized for heart failure: a retrospective cohort study.
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The interaction with NYHA class remained highly significant ( P for interaction <0.001), with the prognostic impact of eGFR < 60 mL/min/1.73 m 2 amplifying stepwise across NYHA class (NYHA III: aOR 1.75; NYHA IV: aOR 2.13).