In the earlier disease setting, the recently presented AMPLITUDE trial in HRRm metastatic castration-sensitive prostate cancer showed that niraparib plus AAP versus placebo plus AAP significantly improved rPFS and showed a trend toward an OS benefit at the first interim analysis [ 30 ].
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From Genomic Testing to Olaparib Treatment: Real-World Utilization and Outcomes in BRCA-Mutated Metastatic Castration-Resistant Prostate Cancer.
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