Identification of novel protein markers and therapeutic targets for common urological cancers by integrating large-scale human plasma proteome with the genome.

Notably, we observed that after multiple correction, the FDR threshold for the protein PSCA in the white British population was close to 0.05, and it exhibited a positive effect direction similar to that in the Finnish population (IVW: OR = 1.173, 95%CI = 1.088–1.264, FDR = 5.01 × 10 –2 ), while the MR analysis for the protein GSTM3 did not reach statistical significance, which may be associated with population differences.

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