Comparative analysis of natural versus ovarian stimulation cycles in intrauterine insemination by diverse infertility indications.

Ann Med · 2026 · PMC13288532 · PMID 42319031

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a numerical trendno p-value reported

However, a numerical trend toward improved clinical pregnancy and live birth outcomes was observed in the natural cycle.

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did not reach statistical significanceno p-value reported

For patients with endometriosis, tubal factor infertility and male factor infertility, NC-IUI showed a potential trend of clinical applicability, while OSC-IUI tended to be more suitable for unexplained infertility; however, these subgroup differences did not reach statistical significance and warrant further validation in larger cohorts.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.