Comparing the efficacy and safety of unilateral versus bilateral spinal anesthesia: a meta-analysis and systematic review.

Ann Med · 2026 · PMC13288713 · PMID 42314657

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did not reach statistical significancep = 0.06so close (0.05 < p ≤ 0.1)

In a combined analysis, although the incidence of bradycardia was lower in unilateral spinal anesthesia than in bilateral spinal anesthesia, the difference did not reach statistical significance (RR = 0.55, 95% CI:0.30–1.02, p = 0.06, I 2 = 0%) ( Figure 8A ).

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