Standardised, telemonitored titration of guideline-directed medical therapy in heart failure is associated with faster optimisation and improved persistence compared to standard of care.

Open Heart · 2026 · PMC13289401 · PMID 42331565

Europe PMC DOI

hedged sentence

0.1230

closest p · 2.5× alpha

0.1230

boldest claim

The sentences

did not reach statistical significancep=0.123not close (p > 0.1)

For SGLT2i, the point estimate was directionally consistent but did not reach statistical significance (OR 8.8, 95% CI 0.6 to 140, p=0.123) ( table 2 ).

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