Barely Significant
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Global burden and time trends of vaccine-preventable diseases in children and adolescents.

Ital J Pediatr · 2026 · PMC13289554 · PMID 42087201

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a significant trendno p-value reported
A linear regression model calculated AAPCs, and a joinpoint regression model identified a significant trend - change years.

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an increasing trendno p-value reported
From 1990 to 2021, 10 countries/areas exhibited an increasing trend.

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a decreasing trendno p-value reported
Moreover, the long-term trend from 1990 to 2021 shows a decreasing trend in all countries/regions (Table 5 ; Fig. 8 ).

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