Bile acid retention in efferocytic macrophages shapes their inflammatory status during cholangitis.

J Exp Med · 2026 · PMC13289589 · PMID 42334420

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Interestingly among the markers analyzed, only CD206 expression, unlike that of the other markers, showed a trend toward regulation by LXR αβ at both protein and mRNA levels, as observed in bone marrow–derived Mφ (BMDMs) isolated from WT or Lxrab −/− mice, either untreated (Untr) or exposed to aH ( Fig.

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