Longitudinal analysis of CYFRA 21-1 levels in patients with pulmonary nodules: Differential trajectories between benign and malignant cases.

PLoS One · 2026 · PMC13289921 · PMID 42335041

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hedged sentence

0.1600

closest p · 3.2× alpha

0.1600

boldest claim

The sentences

did not reach statistical significancep = 0.16not close (p > 0.1)

However, absolute slope was higher in malignant nodules compared to benign nodules: however, this difference did not reach statistical significance (p = 0.16), with an AUC of 0.60 (95% CI 0.48−.87).

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