Barely Significant
← all excerpts

KRAS-driven immune exclusion in pancreatic ductal adenocarcinoma: mechanisms and therapeutic reversal.

Oncologist · 2026 · PMC13290491 · PMID 42226008

Europe PMCDOI
1
hedged sentence
0.0600
closest p · 1.2× alpha
0.0600
boldest claim

The sentences

did not reach statistical significanceP = 0.06so close (0.05 < p ≤ 0.1)
5 Juxtatumoral CD8+ density below 0.05 cells per high-power field was observed in most PDAC cases; tumors at or below this threshold were associated with significantly decreased survival ( P = 0.045), whereas overall stromal CD8+ density did not reach statistical significance for survival ( P = 0.06). 5 These findings demonstrated that cytotoxic T cells were not absent from PDAC but were physically restricted from reaching tumor epithelium, where effector function is critical to antitumor activity.

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.