HDL-mimetic peptide treatment reverses APOE4-induced transcriptomic and lipidomic alterations in the brain of humanized APOE mice.

Alzheimers Dement · 2026 · PMC13290654 · PMID 42337953

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a strong trendno p-value reported

Notably, D4F treatment showed a strong trend to modulate gene co‐expression patterns in E4/4 mice, particularly within the lightcyan and greenyellow module.

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