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Integrating contrast-enhanced ultrasound to optimize margin delineation in Mohs micrographic surgery for primary dermatofibrosarcoma protuberans: a retrospective cohort study.

Front Oncol · 2026 · PMC13290673 · PMID 42358552

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HFUS+CEUS was associated with a reduction in the peripheral margin positivity rate from 38.9% to 5.3% compared with HFUS-only ( P = 0.008; Figure 5D ), although formal interaction testing did not reach statistical significance ( P for interaction = 0.077).

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