Barely Significant
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Effects of Guselkumab on Structural Damage Progression in Patients with Active Psoriatic Arthritis.

Adv Ther · 2026 · PMC13290883 · PMID 42084657

1
hedged sentence
0.0720
closest p · 1.4× alpha
0.0720
boldest claim

The sentences

did not reach statistical significancep = 0.072so close (0.05 < p ≤ 0.1)
LS mean changes from baseline were numerically lower in the Q8W group relative to placebo but did not reach statistical significance (0.52 vs 0.95; p = 0.072) [ 49 ].

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