Association Between GLP-1RAs and Postoperative Complications Following Operative Ankle Fracture Fixation: A Retrospective Cohort Study.

Foot Ankle Orthop · 2026 · PMC13291453 · PMID 42358523

Europe PMC DOI

hedged sentences

0.0080

closest p · 0.2× alpha

0.0080

boldest claim

The sentences

highly significantP = .008actually significant

At 12 months, the GLP-1 cohort demonstrated a highly significant increase in the RD of 0.014 with a 95% CI of 0.004 to 0.024 in nonunion/malunion compared with the control group ( P = .008) ( Table 3 ).

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did not reach statistical significanceno p-value reported

Although the TS suggested potential divergences for wound dehiscence ( P = .019 at 6 months; P = .029 at 12 months) and procedural complications ( P = .038 and t = 2.382 at 6 months; P = .028 and t = 2.093 at 12 months), these findings did not reach statistical significance via LRT or RD ( Tables 2 and 3 ).

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