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Bottlebrush polymer conjugates for enhanced antisense oligonucleotide therapy in myotonic dystrophy type 1.

Nucleic Acids Res · 2026 · PMC13291609 · PMID 42339623

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The free L9 group showed modest correction of 18.7%, consistent with expected LNA ASO exposure in muscle; however this did not reach statistical significance ( Supplementary Fig.

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