Relative to the reserpine group, CMPP 10 mg/kg (p = 0.0426) and CMPP 20 mg/kg (p = 0.0007) significantly increased withdrawal threshold, whereas CMPP 5 mg/kg (p = 0.4241) and gabapentin (p = 0.1681) did not reach statistical significance.
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Therapeutic potential of CMPP, a novel maleimide derivative, in a reserpine-induced mouse model of pain-depression dyad.
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