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Therapeutic potential of CMPP, a novel maleimide derivative, in a reserpine-induced mouse model of pain-depression dyad.

Biochem Biophys Rep · 2026 · PMC13292243 · PMID 42359430

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Relative to the reserpine group, CMPP 10 mg/kg (p = 0.0426) and CMPP 20 mg/kg (p = 0.0007) significantly increased withdrawal threshold, whereas CMPP 5 mg/kg (p = 0.4241) and gabapentin (p = 0.1681) did not reach statistical significance.

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