nominally significantp = 0.030
In contrast, limited coordinated immune remodeling was observed between CB and NCB patients; only one population, CD3 + CD8 + PD-1 + PD-L1 + T cells, showed a nominally significant ( p = 0.030, q = 0.87, Wilcoxon rank-sum test) increase following treatment, preferentially in NCB patients ( Figure 5 B).