Efficacy and safety of hyperthermic intraperitoneal chemotherapy in treatment of primary or recurrent ovarian cancer: systematic review and meta-analysis.

Front Med (Lausanne) · 2026 · PMC13294293 · PMID 42369161

Europe PMC DOI

hedged sentences

0.0830

closest p · 1.7× alpha

0.0830

boldest claim

The sentences

marginally significantp = 0.083so close (0.05 < p ≤ 0.1)

recurrent) showed a marginally significant association (HR = 0.480; 95% CI: 0.209–1.101; p = 0.083; R 2 = 100%), suggesting that the direction and magnitude of HIPEC’s effect on progression-related outcomes may differ between primary and recurrent settings.

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did not reach statistical significanceno p-value reported

However, this finding did not reach statistical significance at the α = 0.05 level.

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