A retrospective and in silico study on the augmentation of risperidone in the treatment of adolescent treatment-resistant depression: efficacy evaluation, adverse reaction analysis, and molecular mechanistic insights.

Front Chem · 2026 · PMC13294303 · PMID 42369651

Europe PMC DOI

hedged sentence

0.3100

closest p · 6.2× alpha

0.3100

boldest claim

The sentences

did not reach statistical significancep = 0.31not close (p > 0.1)

53.8%) compared with the low-dose group, although these differences did not reach statistical significance (p = 0.31 and p = 0.35, respectively).

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