Pharmacological Characterization of SLL-022CCP, a Selective κ‑Opioid Receptor Agonist with Potent Antinociceptive Effects and Low Central Side Effects.

ACS Omega · 2026 · PMC13294904 · PMID 42368158

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

did not reach statistical significanceno p-value reported

SLL-022CCP at 0.1–0.32 mg/kg showed a dose-dependently trend toward increasing nesting behaviors, although these effects did not reach statistical significance compared to the saline group.

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.