Chronic Obstructive Pulmonary Disease Influence on Lung Cancer Risk Through Blood Metabolite Mediation: A Two-Sample Mendelian Randomisation and Mediation Analysis.

Int J Chron Obstruct Pulmon Dis · 2026 · PMC13295007 · PMID 42367346

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hedged sentence

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closest p · 1.0× alpha

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boldest claim

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nominally significantP < 0.05actually significant

Moreover, 113 blood metabolites and six inflammatory factors showed nominally significant causal associations with LC risk ( P < 0.05).

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