REG3A: A Potential Fecal Biomarker for Ulcerative Colitis.

Mediators Inflamm · 2026 · PMC13296221 · PMID 42345560

Europe PMC DOI

hedged sentences

0.0640

closest p · 1.3× alpha

0.0680

boldest claim

The sentences

did not reach statistical significancep = 0.064so close (0.05 < p ≤ 0.1)

FC showed discriminatory power (AUC = 0.717 [CI: 0.563–0.871], p = 0.014), while REG3A alone did not reach statistical significance (AUC = 0.663 [CI: 0.494–0.833], p = 0.064).

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a nonsignificant trendp = 0.068so close (0.05 < p ≤ 0.1)

However, a nonsignificant trend was observed, with the combination model showing the highest AUC value [AUC = 0.662 (CI: 0.499–0.826), p = 0.068], followed by FC [AUC = 0.665 (CI: 0.488–0.822), p = 0.082] and REG3A [AUC = 0.619 (CI: 0.440–0.798), p = 0.181] (Figure 3 c).

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