Effects of Vitamin B6 and Folic Acid on Cardiometabolic Biomarkers and Cardiac Oxidative Stress in Homocysteine-Loaded Rats.

Biomedicines · 2026 · PMC13296511 · PMID 42351801

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0600

boldest claim

The sentences

highly significantp < 0.001actually significant

Vitamin B12 showed a more complex pattern, with significant main effects of both Hcy ( p = 0.002) and B6+FA supplementation ( p = 0.002), as well as a highly significant Hcy × B6+FA interaction ( p < 0.001).

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did not reach statistical significancep = 0.060so close (0.05 < p ≤ 0.1)

Left ventricular wall thickness showed a significant main effect of B6+FA supplementation ( p = 0.024), whereas the Hcy effect approached but did not reach statistical significance ( p = 0.060), and the interaction was not significant ( p = 0.767).

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