Engineering Halomonas bluephagenesis TD01 as a Robust Chassis for the Sustainable Production of Hyaluronic Acid

Biomolecules · 2026 · PMC13296553

Europe PMC

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highly significantno p-value reported

For the HA and cell biomass values, the p -value (0.0001) is highly significant, R 2 (coefficient determination) is 93.52%, 99.53%, and the adjusted R 2 = 90.81% and 99.43%, respectively.

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did not reach statistical significanceno p-value reported

In contrast, temperature (B, p = 0.190), incubation time (D, p = 0.722), and agitation rate (F, p = 0.463) did not reach statistical significance as individual model terms.

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