Despite a medium to large effect size (Cohen’s d = 0.72), this difference did not reach statistical significance ( p = 0.087), which the authors directly attribute to a lack of statistical power resulting from the premature termination of the study and recruitment due to the COVID-19 pandemic.
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Pharmacotherapeutic Options in Drug-Resistant Bipolar Depression: From Molecular Mechanisms to Rational Polypharmacotherapy
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0.0870
0.0870
The sentences
A highly significant indicator is the fact that 36% of patients achieved complete remission of depressive symptoms just 40 min after intravenous administration.