A Primate-Specific lncRNA LINC01021 Contributes to Cellular and Organismal Aging via DAZAP1-Dependent Destabilization of RBMX.

Aging Cell · 2026 · PMC13297028 · PMID 42348295

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did not reach statistical significanceno p-value reported

This analysis revealed a significantly elevated senescence signal in young adult KI/KI mice compared with WT controls, whereas aged KI mice exhibited a trend toward increased signal intensity that did not reach statistical significance (Figures 6D,E and S5C , D ), suggesting that LINC01021 expression may contribute to the onset of cellular senescence in vivo.

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