Barely Significant
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Neoadjuvant Immunotherapy-Based Treatment Versus Chemotherapy Alone in Resectable Locally Advanced dMMR/MSI-H Gastric Cancer: A Real-World Study with Meta-Analysis

Cancers (Basel) · 2026 · PMC13297142

1
hedged sentence
0.0600
closest p · 1.2× alpha
0.0600
boldest claim

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did not reach statistical significancep = 0.06so close (0.05 < p ≤ 0.1)
Sensitivity analyses restricted to the three studies (n = 127) assessed as low risk of bias demonstrated that patients in group A had a 3.80-fold higher pCR rate and a 6.50-fold higher MPR rate compared with those in group B ( Figure S3 ); however, these differences did not reach statistical significance, likely attributable to limited statistical power ( p = 0.06 for pCR; p = 0.08 for MPR).

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