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Clinical Performance of BIO-S and BIO-SC Composite Bioscores for 28-Day Mortality Stratification in Adults with Sepsis and Septic Shock

Biomedicines · 2026 · PMC13297196

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BIO-S also showed significantly higher discrimination than SOFA and APACHE II, whereas the difference between BIO-S and SOFA plus CCI did not reach statistical significance.

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