Nonlinear EEG Complexity as a Marker of Maladaptive Brain Plasticity in Substance Use Disorders: A Multi-Group Machine Learning Classification Study.

Brain Sci · 2026 · PMC13297297 · PMID 42352612

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a clear trendno p-value reported

A clear trend was observed where the control group consistently exhibited higher values of LLE, FD, HE, and KC across most channels.

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an increasing trendno p-value reported

It is noteworthy that various studies have identified an increasing trend in can users’ complexity, which can be inferred from Figure 2 that FD values for the can user in all groups, H-can, meth-can and MD have increased complexity at the frontal lobes as compared to control and other groups. 4.2.

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