Tumour Mutational Burden and Its Relationship with Clinical Outcomes in Locally Advanced and Recurrent/Metastatic Adenoid Cystic Carcinoma with and Without NOTCH Pathway Activation.

In the MSK cohort, the same trend towards shorter OS was seen in tumours with NOTCH1/2-activting mutations, but this did not reach statistical significance (median OS 1.6 years vs. 2.4 years, p = 0.7) ( Figure 2 B). 3.4.

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