Long-Term Risk Trajectories of Diabetes Differ After Direct-Acting Antiviral and Interferon Therapy in Chronic Hepatitis C: A Real-World Cohort Study

Biomedicines · 2026 · PMC13297605

Europe PMC

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0.1900

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0.1900

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did not reach statistical significancep = 0.19not close (p > 0.1)

In patients with fibrosis ( N = 306), the overall T2DM incidence was 7.52%, with a higher rate in the IFN-based group (11.22%) than in the DAA-based group (5.77%), but this difference did not reach statistical significance (IRR 2.22, 95% CI, 0.73–7.10; p = 0.19).

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