Beyond Linear Risk: A U-Shaped Association Between Platelet Reactivity and Mortality in Coronary Artery Disease.

Diseases · 2026 · PMC13298364 · PMID 42346287

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hedged sentences

0.0980

closest p · 2.0× alpha

0.4910

boldest claim

The sentences

borderline significancep = 0.098so close (0.05 < p ≤ 0.1)

Obstructive CAD demonstrated borderline significance (OR: 1.46 (95% CI: 0.93–2.31); p = 0.098) ( Table 2 ). 3.2.

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did not reach statistical significancep = 0.491not close (p > 0.1)

Although overall quartile differences did not reach statistical significance ( p = 0.491), the bimodal pattern—with mortality peaks at both extremes of the PRU distribution—was numerically pronounced and clinically meaningful ( Table A4 ).

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