ACT comparison, the following genes were nominally significant at FDR < 0.05: SQLE (log 2 FC = +3.02, p adj = 0.008), ACACA (log 2 FC = +1.18, p adj = 0.004), HMGCR (HMG-CoA reductase; log 2 FC = +1.49, p adj = 0.033), and LDLRAP1 (log 2 FC = +3.05, p adj = 0.049); at the relaxed FDR < 0.10 threshold, CETP (log 2 FC = −1.29, p adj = 0.094), PPARG (log 2 FC = −1.34, p adj = 0.083), SCD5 (log 2 FC = +1.19, p adj = 0.100), and FASN (log 2 FC = +0.95, p adj = 0.059) were additionally flagged.
← all excerpts
Lipid Metabolic Reprogramming and Epigenetic Co-Dysregulation Across the Central Chondrosarcoma Grade Spectrum: A Multi-Cohort RNA-seq Study
1
—
—