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Pubertal development and hypothalamic-pituitary-gonadal axis are altered in male mice lacking Mecp2.

J Neuroendocrinol · 2026 · PMC13301260 · PMID 42349852

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hedged sentence
0.0600
closest p · 1.2× alpha
0.0600
boldest claim

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showed a trendp = .06so close (0.05 < p ≤ 0.1)
Surprisingly, we found that relative circulating levels of GnRH showed a trend towards reduction in Mecp2 CD1 ‐null as compared to WT males ( t 12 = 2.08; p = .06; Figure 4A ).

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